Ortiz-Catalan M., Guðmundsdóttir R.A., Kristoffersen M.B., Zepeda-Echavarria A., Caine-Winterberger K., Kulbacka-Ortiz K., Widehammar C., Eriksson K., Stockselius A., Ragnö C., Pihlar Z., Burger H., and Hermansson L., Phantom motor execution facilitated by machine learning and augmented reality as treatment for phantom limb pain: a single group, clinical trial in patients with chronic intractable phantom limb pain, The Lancet, 2016, 388:2885-2894.
Description
Phantom limb pain (PLP) is a debilitating condition common after amputation that can considerably hinder patients' quality of life. Several treatments have reported promising results in alleviating PLP. However, clinical evaluations are usually performed in small cohorts and rigorous clinical trials are scarce. In addition, the underlying mechanisms by which novel interventions alleviate PLP are often unclear, potentially because the condition itself is poorly understood. This article presents a theoretical framework of PLP that can be used as groundwork for hypotheses of novel treatments.
Ksenchyna K., Kristoffersen MB, McGowan E., Limakatso K., Kovalenko S., Dmytriiev D., and Ortiz-Catalan M., Myoelectric and Progressive Motor Training for Phantom Limb Pain in People with Amputations During War: A Feasibility Report, Journal of Pain Research. 2026.
DOI: 10.2147/JPR.S578370
Description
Phantom limb pain (PLP) is a debilitating condition common after amputation that can considerably hinder patients' quality of life. Several treatments have reported promising results in alleviating PLP. However, clinical evaluations are usually performed in small cohorts and rigorous clinical trials are scarce. In addition, the underlying mechanisms by which novel interventions alleviate PLP are often unclear, potentially because the condition itself is poorly understood. This article presents a theoretical framework of PLP that can be used as groundwork for hypotheses of novel treatments.
Munoz-Novoa M., van Veldhoven J., Postema S., Kristoffersen M.B., Keesom E., Lendaro E., Lidstrom-Holmqvist K., Ortiz-Catalan M., and van der Sluis C., Regaining the intention to live after relief of intractable phantom limb pain: a case study. Scandinavian Journal of Pain, 2025, 25(1): 20250006.
Description
Phantom limb pain (PLP) is a debilitating condition common after amputation that can considerably hinder patients' quality of life. Several treatments have reported promising results in alleviating PLP. However, clinical evaluations are usually performed in small cohorts and rigorous clinical trials are scarce. In addition, the underlying mechanisms by which novel interventions alleviate PLP are often unclear, potentially because the condition itself is poorly understood. This article presents a theoretical framework of PLP that can be used as groundwork for hypotheses of novel treatments.
Lendaro E., Hermanson L., Van der Sluis C., Hermansson L., Bunketorp-Käll L., Burger H., Keesom E., Widehammar C., Munoz-Novoa M., McGuire B., O’Reilly P., Earley E., Iqbal S., Kristoffersen M., Stockselius A., Gudmundson L., Hill W., Diers M., Turner K., Weiss T., and Ortiz-Catalan M., Extended Reality used in the Treatment of Phantom Limb Pain: A Multicenter, Double-blind, Randomized Controlled Trial, PAIN, 2025, 166(3):571-586.
Description
Phantom limb pain (PLP) is a debilitating condition common after amputation that can considerably hinder patients' quality of life. Several treatments have reported promising results in alleviating PLP. However, clinical evaluations are usually performed in small cohorts and rigorous clinical trials are scarce. In addition, the underlying mechanisms by which novel interventions alleviate PLP are often unclear, potentially because the condition itself is poorly understood. This article presents a theoretical framework of PLP that can be used as groundwork for hypotheses of novel treatments.
Munoz-Novoa M, Kristoffersen MB, Sunnerhagen KS, Naber A, Ortiz-Catalan M.* & Alt Murphy M*. Myoelectric pattern recognition with virtual reality and serious gaming improves upper limb function in chronic stroke: A single case experimental design study. Journal of NeuroEngineering and Rehabilitation. 2025, 22(6). *Senior Authors.
Description
Phantom limb pain (PLP) is a debilitating condition common after amputation that can considerably hinder patients' quality of life. Several treatments have reported promising results in alleviating PLP. However, clinical evaluations are usually performed in small cohorts and rigorous clinical trials are scarce. In addition, the underlying mechanisms by which novel interventions alleviate PLP are often unclear, potentially because the condition itself is poorly understood. This article presents a theoretical framework of PLP that can be used as groundwork for hypotheses of novel treatments.